The presentation will discuss the interaction between the immunological factors of colostrum (antibodies, cells and their products, and microbiota) and the naive neonatal immune system, which results in the programming of the immune system at the onset of life, with short- and long-term consequences.
Bartonellosis is associated with a wide range of disease syndromes in various mammalian species, including transient cat-scratch disease, fever with bacteremia, endocarditis, and others. Host immune function seems to play a role in the clinical presentation and progression of bartonellosis, though this is less well described in dogs and cats than in people. This presentation will focus on the Bartonella species that most commonly infect cats, dogs, and humans, reviewing the current state of knowledge from in vitro and in vivo research on the immune response to infection. We will discuss the molecular and immunological mechanisms of host invasion and intracellular persistence, as well as host immune escape and the consequences thereof.